United States - English - NLM (National Library of Medicine)

ani pharmaceuticals, inc. - cyclophosphamide (unii: 8n3dw7272p) (cyclophosphamide anhydrous - unii:6uxw23996m) - cyclophosphamide anhydrous 50 mg - cyclophosphamide capsules are indicated for the treatment of: cyclophosphamide capsules, although effective alone in susceptible malignancies, is more frequently used concurrently or sequentially with other antineoplastic drugs. cyclophosphamide capsules are indicated for the treatment of biopsy proven minimal change nephrotic syndrome in pediatric patients who failed to adequately respond to or are unable to tolerate adrenocorticosteroid therapy. limitations of use: the safety and effectiveness of cyclophosphamide capsules for the treatment of nephrotic syndrome in adults or other renal disease has not been established. cyclophosphamide capsules are contraindicated in patients with: risk summary based on its mechanism of action and published reports of effects in pregnant patients or animals, cyclophosphamide capsules can cause fetal harm when administered to a pregnant woman [see clinical pharmacology (12.1) and nonclinical toxicology (13.1) ]. exposure to cyclophosphamide during pregnancy may cause fetal

Malta - English - Medicines Authority

baxter healthcare limited - cyclophosphamide - powder for solution for injection - cyclophosphamide 500 mg - antineoplastic agents

Malta - English - Medicines Authority

baxter healthcare limited - cyclophosphamide - powder for solution for injection - cyclophosphamide 1 g - antineoplastic agents

Malta - English - Medicines Authority

baxter healthcare limited - cyclophosphamide - coated tablet - cyclophosphamide 50 mg - antineoplastic agents

Malta - English - Medicines Authority

accord healthcare ireland ltd euro house, euro business park, little island cork, t45 k857, ireland - cyclophosphamide - powder for solution for infusion or injection - cyclophosphamide 500 mg - antineoplastic agents

Australia - English - Department of Health (Therapeutic Goods Administration)

accord healthcare pty ltd - cyclophosphamide, quantity: 2000 mg (equivalent: cyclophosphamide monohydrate, qty mg) - injection, powder for - excipient ingredients: mannitol - the proper use of cyclophosphamide requires accurate diagnosis, careful assessment of the anatomic extent of the disease, knowledge of the type and effects of any previous therapy, and continued evaluation of the patient?s general and haematologic status. it is essential that adequate clinical and laboratory facilities be available for proper monitoring of patients during treatment with cyclophosphamide.,the clinical course of the disease should be recorded in objective terms before treatment is begun and thereafter at regular intervals. careful management of patients receiving cyclophosphamide will help achieve maximum benefit with minimum risk.,antineoplastic properties patients with neoplasms that might preferably be treated by surgical and/or irradiation procedures should ordinarily not be treated by chemotherapy alone.,the following classification is a guide to the various neoplastic conditions in which benefit may be derived from chemotherapy with cyclophosphamide:,frequently responsive myeloproliferative and lymphoproliferative disorders: malignant lymphomas including hodgkins (stages iii and iv, peter?s staging system*) and non-hodgkins lymphomas; multiple myeloma; leukaemias; mycosis fungoides (advanced disease).,stage i: disease limited to one anatomic region (stage i) or two contiguous anatomic regions (stage i2) on the same side of the diaphragm.,* modified as the international staging classification for hodgkin?s disease in ?report of the committee on the staging of hodgkin?s disease?. cancer res 26:1310, 1966.,stage ii: disease in more than two anatomic regions or two contiguous regions on the same side of the diaphragm.,stage iii: disease on both sides of the diaphragm, but not extending beyond the involvement of lymph nodes, spleen, and/or waldeyer?s ring.,stage iv: involvement of the bone marrow, lung parenchyma, pleura, liver, bone, skin, kidneys, gastrointestinal tract, or in any tissue or organ in addition to lymph nodes, spleen or waldeyer?s ring.,all stages are subclassified as a or b to indicate the absence or presence, respectively, of systemic symptoms.,frequently responsive solid malignancies: neuroblastoma (patients with disseminated disease); adenocarcinoma of the ovary, retinoblastoma.,infrequently responsive malignancies: carcinoma of the breast; malignant neoplasms of the lung.,immunosuppressive properties,cyclophosphamide has also been used in the treatment of autoimmune diseases and immunopathies of unspecified type (ie wegener?s granulomatosis) when these diseases have been resistant to conventional first and second line of treatment, and for the prevention of transplant rejection. cyclophosphamide can be recommended for use in treatment of nonmalignancies only when in the opinion of the physician the benefits to the patient outweigh the risk of treatment with cyclophosphamide.

Australia - English - Department of Health (Therapeutic Goods Administration)

accord healthcare pty ltd - cyclophosphamide, quantity: 500 mg (equivalent: cyclophosphamide monohydrate, qty mg) - injection, powder for - excipient ingredients: mannitol - the proper use of cyclophosphamide requires accurate diagnosis, careful assessment of the anatomic extent of the disease, knowledge of the type and effects of any previous therapy, and continued evaluation of the patient?s general and haematologic status. it is essential that adequate clinical and laboratory facilities be available for proper monitoring of patients during treatment with cyclophosphamide.,the clinical course of the disease should be recorded in objective terms before treatment is begun and thereafter at regular intervals. careful management of patients receiving cyclophosphamide will help achieve maximum benefit with minimum risk.,antineoplastic properties patients with neoplasms that might preferably be treated by surgical and/or irradiation procedures should ordinarily not be treated by chemotherapy alone.,the following classification is a guide to the various neoplastic conditions in which benefit may be derived from chemotherapy with cyclophosphamide:,frequently responsive myeloproliferative and lymphoproliferative disorders: malignant lymphomas including hodgkins (stages iii and iv, peter?s staging system*) and non-hodgkins lymphomas; multiple myeloma; leukaemias; mycosis fungoides (advanced disease).,stage i: disease limited to one anatomic region (stage i) or two contiguous anatomic regions (stage i2) on the same side of the diaphragm.,* modified as the international staging classification for hodgkin?s disease in ?report of the committee on the staging of hodgkin?s disease?. cancer res 26:1310, 1966.,stage ii: disease in more than two anatomic regions or two contiguous regions on the same side of the diaphragm.,stage iii: disease on both sides of the diaphragm, but not extending beyond the involvement of lymph nodes, spleen, and/or waldeyer?s ring.,stage iv: involvement of the bone marrow, lung parenchyma, pleura, liver, bone, skin, kidneys, gastrointestinal tract, or in any tissue or organ in addition to lymph nodes, spleen or waldeyer?s ring.,all stages are subclassified as a or b to indicate the absence or presence, respectively, of systemic symptoms.,frequently responsive solid malignancies: neuroblastoma (patients with disseminated disease); adenocarcinoma of the ovary, retinoblastoma.,infrequently responsive malignancies: carcinoma of the breast; malignant neoplasms of the lung.,immunosuppressive properties,cyclophosphamide has also been used in the treatment of autoimmune diseases and immunopathies of unspecified type (ie wegener?s granulomatosis) when these diseases have been resistant to conventional first and second line of treatment, and for the prevention of transplant rejection. cyclophosphamide can be recommended for use in treatment of nonmalignancies only when in the opinion of the physician the benefits to the patient outweigh the risk of treatment with cyclophosphamide.

Australia - English - Department of Health (Therapeutic Goods Administration)

accord healthcare pty ltd - cyclophosphamide, quantity: 1000 mg (equivalent: cyclophosphamide monohydrate, qty mg) - injection, powder for - excipient ingredients: mannitol - the proper use of cyclophosphamide requires accurate diagnosis, careful assessment of the anatomic extent of the disease, knowledge of the type and effects of any previous therapy, and continued evaluation of the patient?s general and haematologic status. it is essential that adequate clinical and laboratory facilities be available for proper monitoring of patients during treatment with cyclophosphamide.,the clinical course of the disease should be recorded in objective terms before treatment is begun and thereafter at regular intervals. careful management of patients receiving cyclophosphamide will help achieve maximum benefit with minimum risk.,antineoplastic properties patients with neoplasms that might preferably be treated by surgical and/or irradiation procedures should ordinarily not be treated by chemotherapy alone.,the following classification is a guide to the various neoplastic conditions in which benefit may be derived from chemotherapy with cyclophosphamide:,frequently responsive myeloproliferative and lymphoproliferative disorders: malignant lymphomas including hodgkins (stages iii and iv, peter?s staging system*) and non-hodgkins lymphomas; multiple myeloma; leukaemias; mycosis fungoides (advanced disease).,stage i: disease limited to one anatomic region (stage i) or two contiguous anatomic regions (stage i2) on the same side of the diaphragm.,* modified as the international staging classification for hodgkin?s disease in ?report of the committee on the staging of hodgkin?s disease?. cancer res 26:1310, 1966.,stage ii: disease in more than two anatomic regions or two contiguous regions on the same side of the diaphragm.,stage iii: disease on both sides of the diaphragm, but not extending beyond the involvement of lymph nodes, spleen, and/or waldeyer?s ring.,stage iv: involvement of the bone marrow, lung parenchyma, pleura, liver, bone, skin, kidneys, gastrointestinal tract, or in any tissue or organ in addition to lymph nodes, spleen or waldeyer?s ring.,all stages are subclassified as a or b to indicate the absence or presence, respectively, of systemic symptoms.,frequently responsive solid malignancies: neuroblastoma (patients with disseminated disease); adenocarcinoma of the ovary, retinoblastoma.,infrequently responsive malignancies: carcinoma of the breast; malignant neoplasms of the lung.,immunosuppressive properties,cyclophosphamide has also been used in the treatment of autoimmune diseases and immunopathies of unspecified type (ie wegener?s granulomatosis) when these diseases have been resistant to conventional first and second line of treatment, and for the prevention of transplant rejection. cyclophosphamide can be recommended for use in treatment of nonmalignancies only when in the opinion of the physician the benefits to the patient outweigh the risk of treatment with cyclophosphamide.

Australia - English - Department of Health (Therapeutic Goods Administration)

accord healthcare pty ltd - cyclophosphamide, quantity: 2000 mg (equivalent: cyclophosphamide monohydrate, qty mg) - injection, powder for - excipient ingredients: mannitol - the proper use of cyclophosphamide requires accurate diagnosis, careful assessment of the anatomic extent of the disease, knowledge of the type and effects of any previous therapy, and continued evaluation of the patient?s general and haematologic status. it is essential that adequate clinical and laboratory facilities be available for proper monitoring of patients during treatment with cyclophosphamide.,the clinical course of the disease should be recorded in objective terms before treatment is begun and thereafter at regular intervals. careful management of patients receiving cyclophosphamide will help achieve maximum benefit with minimum risk.,antineoplastic properties patients with neoplasms that might preferably be treated by surgical and/or irradiation procedures should ordinarily not be treated by chemotherapy alone.,the following classification is a guide to the various neoplastic conditions in which benefit may be derived from chemotherapy with cyclophosphamide:,frequently responsive myeloproliferative and lymphoproliferative disorders: malignant lymphomas including hodgkins (stages iii and iv, peter?s staging system*) and non-hodgkins lymphomas; multiple myeloma; leukaemias; mycosis fungoides (advanced disease).,stage i: disease limited to one anatomic region (stage i) or two contiguous anatomic regions (stage i2) on the same side of the diaphragm.,* modified as the international staging classification for hodgkin?s disease in ?report of the committee on the staging of hodgkin?s disease?. cancer res 26:1310, 1966.,stage ii: disease in more than two anatomic regions or two contiguous regions on the same side of the diaphragm.,stage iii: disease on both sides of the diaphragm, but not extending beyond the involvement of lymph nodes, spleen, and/or waldeyer?s ring.,stage iv: involvement of the bone marrow, lung parenchyma, pleura, liver, bone, skin, kidneys, gastrointestinal tract, or in any tissue or organ in addition to lymph nodes, spleen or waldeyer?s ring.,all stages are subclassified as a or b to indicate the absence or presence, respectively, of systemic symptoms.,frequently responsive solid malignancies: neuroblastoma (patients with disseminated disease); adenocarcinoma of the ovary, retinoblastoma.,infrequently responsive malignancies: carcinoma of the breast; malignant neoplasms of the lung.,immunosuppressive properties,cyclophosphamide has also been used in the treatment of autoimmune diseases and immunopathies of unspecified type (ie wegener?s granulomatosis) when these diseases have been resistant to conventional first and second line of treatment, and for the prevention of transplant rejection. cyclophosphamide can be recommended for use in treatment of nonmalignancies only when in the opinion of the physician the benefits to the patient outweigh the risk of treatment with cyclophosphamide.

Australia - English - Department of Health (Therapeutic Goods Administration)

accord healthcare pty ltd - cyclophosphamide, quantity: 1000 mg (equivalent: cyclophosphamide monohydrate, qty mg) - injection, powder for - excipient ingredients: mannitol - the proper use of cyclophosphamide requires accurate diagnosis, careful assessment of the anatomic extent of the disease, knowledge of the type and effects of any previous therapy, and continued evaluation of the patient?s general and haematologic status. it is essential that adequate clinical and laboratory facilities be available for proper monitoring of patients during treatment with cyclophosphamide.,the clinical course of the disease should be recorded in objective terms before treatment is begun and thereafter at regular intervals. careful management of patients receiving cyclophosphamide will help achieve maximum benefit with minimum risk.,antineoplastic properties patients with neoplasms that might preferably be treated by surgical and/or irradiation procedures should ordinarily not be treated by chemotherapy alone.,the following classification is a guide to the various neoplastic conditions in which benefit may be derived from chemotherapy with cyclophosphamide:,frequently responsive myeloproliferative and lymphoproliferative disorders: malignant lymphomas including hodgkins (stages iii and iv, peter?s staging system*) and non-hodgkins lymphomas; multiple myeloma; leukaemias; mycosis fungoides (advanced disease).,stage i: disease limited to one anatomic region (stage i) or two contiguous anatomic regions (stage i2) on the same side of the diaphragm.,* modified as the international staging classification for hodgkin?s disease in ?report of the committee on the staging of hodgkin?s disease?. cancer res 26:1310, 1966.,stage ii: disease in more than two anatomic regions or two contiguous regions on the same side of the diaphragm.,stage iii: disease on both sides of the diaphragm, but not extending beyond the involvement of lymph nodes, spleen, and/or waldeyer?s ring.,stage iv: involvement of the bone marrow, lung parenchyma, pleura, liver, bone, skin, kidneys, gastrointestinal tract, or in any tissue or organ in addition to lymph nodes, spleen or waldeyer?s ring.,all stages are subclassified as a or b to indicate the absence or presence, respectively, of systemic symptoms.,frequently responsive solid malignancies: neuroblastoma (patients with disseminated disease); adenocarcinoma of the ovary, retinoblastoma.,infrequently responsive malignancies: carcinoma of the breast; malignant neoplasms of the lung.,immunosuppressive properties,cyclophosphamide has also been used in the treatment of autoimmune diseases and immunopathies of unspecified type (ie wegener?s granulomatosis) when these diseases have been resistant to conventional first and second line of treatment, and for the prevention of transplant rejection. cyclophosphamide can be recommended for use in treatment of nonmalignancies only when in the opinion of the physician the benefits to the patient outweigh the risk of treatment with cyclophosphamide.